Hormone replacement therapy (HRT) Hormone replacement therapy (HRT) is used for osteoporosis in women at risk of fractures and menopausal symptoms. Learn how it works, risks and side-effects. Hyaluronan injections Hyaluronan injections are used to treat osteoarthritis. Learn how they work, how long they take, risks and side-effects. Hydroxychloroquine Hydroxychloroquine is a disease-modifying anti-rheumatic drug (DMARD) used for rheumatoid arthritis and lupus. Learn how long it takes, risks and side-effects.