Raynaud's phenomenon Raynaud’s phenomenon causes hands and feet to change colour and become painful under cold or stressful conditions. Learn the symptoms, causes and treatment. Reactive arthritis Reactive arthritis can develop following an infection of the bowel or genital tract, causing painful, swollen joints. Learn the causes, symptoms and treatments. Rheumatoid arthritis (RA) Rheumatoid arthritis is the UK’s second most common arthritis. It causes joint pain and inflammation. Learn about the symptoms, causes and treatment.